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Chicago White Sox's Philip Humber throws 21st perfect game in major league history

It was baseball's 21st perfect game and first since Philadelphia's Roy Halladay threw one against the Florida Marlins on May 29, 2010. It was the third in White Sox's history, joining Mark Buehrle against Tampa Bay on July 23, 2009, and Charles Robertson against Detroit on April 30, 1922.

With the White Sox lined up on the top step of the dugout, Humber fell behind 3-0 to Michael Saunders leading off the ninth. But he rebounded to strike him out. John Jaso then flied out before Brendan Ryan, another pinch-hitter, struck out to end the game.

-- Reported by the Associated Press

Elaine Thompson / AP

Chicago White Sox starting pitcher Philip Humber, center, is mobbed by teammates after pitching a perfect game against the Seattle Mariners, April 21, in Seattle. The White Sox won 4-0.

Related content: Slideshow of perfect games over the years

White Sox pitcher Philip Humber tossed a perfect game on Saturday against the Seattle Mariners. NBC's Lester Holt reports.